SciBerg is a private research company located near the city of Heidelberg, a center of European bioinformatics and life sciences. We integrate a group of PhD-holding scientists working in the world's leading research institutions and having profound expertise in experimental design and analysis of various high-throughput sequencing data. Some of our specialists have a proven record of prior developing the novel NGS library preparation methods (such as CATS Technology) as well as various data analysis pipelines.
Besides providing commercial services, we participate in various fundamental and applied research projects together with academic and industrial partners on a not-for-profit basis. Our primary research interests are focused on developing novel experimental procedures and bioinformatic pipelines for precision medicine, as well as for non-invasive diagnosis/prognosis of human diseases using extracellular circulating nucleic acids.
Currently, there are various strategies and workflows developed for the analysis of high-throughput sequencing data and their number is mounting. We are constantly testing the newly emerging bioinformatics pipelines to ensure that your data are processed with the most reliable and accurate algorithms. We apply predominantly open-source and only freely available software packages working under Unix/Linux and R/Bioconductor environments.
The software used for the analysis of high-throughput sequencing data is continuously being updated and improved. At the same time, certain widely used NGS bioinformatics pipelines (including cloud-based) may include outdated or obsolete software packages what may lead to inaccurate results. We utilize only up-to-date and thoroughly tested software packages as well as the most recent versions of reference genomes/transcriptomes.
Most NGS projects require individual data analysis approaches rather than standard solutions. Frequently, such studies need substantial customization that may include preparation of custom reference databases, applying distinct parameters for the alignment and reads counting, specific methods for statistical analyses and efficient visualization strategies. Furthermore, depending on the outcome of the "default" analysis workflows, additional tasks deviating from the original plan may arise. Along with standard options, we offer fully customized bioinformatics services specifically tailored for your project.
Outsourcing the NGS data analysis services is almost always more cost-efficient than maintaining an in-house bioinformatics facility. By using our services, your expenses for the data analysis will constitute only a fraction out of total price incurred for the DNA library preparation and deep sequencing. Besides, we ensure that your NGS data analysis will be performed by a PhD-holding data scientist with a proved record of academic achievements and relevant experience.