When PCR duplicates should be removed

When PCR duplicates should be removed?

DNA-seq (WGS, WES)

ONLY IN CASE OF PAIRED-END RUNS

BS-seq (WGBS, RRBS)

ONLY IN CASE OF PAIRED-END RUNS

WTS RNA-seq

ONLY IN CASE OF PAIRED-END RUNS

mRNA-seq

ONLY IN CASE OF PAIRED-END RUNS

scRNA-seq

NEVER

small RNA-seq

NEVER

ChIP-seq

NEVER

Amplicon sequencing

NEVER

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